Your biggest problem right now is that you've got a lot of regions that simply cannot be held in a game, either because they are too big, have too many borders, or both. These are my suggestions to combat that issue:
You need to divide the US into two regions, west and east. Rocky Mountains and SW States plus everything west of that is one, everything to the east is the other.
You also need to divide Amazonia into two regions. Guyana and all the purple territories south of that and east of Peru are one, the rest are the other.
You need to reform all of the Brazil territories. Use this as a guide (Combine the yellow and red regions into one territory):
http://www.arrl.org/news/stories/2003/1 ... ap-lrg.gif
Ignore the Spanish names they give you, just call it North Brazil, NE Brazil, etc., or find other English names.
Eliminate the connection between Hawaii and Baja.
Add mountains across the south border of British Columbia, BC now only borders Manitoba and Yukon.
Move the Manitoba/Ontario border slightly east so that it's clear Ontario doesn't border North Central.
Make it more clear that the Great Lakes divide those territories. The only connections between Canada and Eastern US should be North Central-Manitoba and New England-Quebec.
Change the river in Western US to divide Pacific US and Baja. Baja should now only border Sierra Madre.
Move the Galapagos-Guatamala connection to be Galapagos-Sierra Madre.
Eliminate the S. Georgia-Brazil connection.
Change the Nuuk-Brazil connection to Nuuk-Guyana.
Move the army circle off of the Galapagos Islands so that you can more easily see what color region it is a part of.
Are Pacific Alaska and Arctic Alaska actually divided by that river? If so, why? If not, why is that river there?
I may have more later, but that's what I see for now.