Psychiatry

[DoomYoshi]

A MUST-READ article:
https://www.psychologytoday.com/ca/blog ... n-debunked

The serotonin hypothesis of depression, popular from the 1990s until now, is false, and has been known to be false for a long time, and never was proven to begin with. The norepinephrine hypothesis of depression, which preceded the serotonin hypothesis in the 1960s to the 1980s, also was false, and has been known to be false for a long time, and never was proven to begin with. The same holds for the dopamine hypothesis of schizophrenia, which began in the 1960s and 1970s, and more generally for the “chemical imbalance” metaphor for all mental illness.

The problem is that DSM diagnoses are not biologically valid because they are not scientifically based; they are not based solely on scientific evidence but rather are social constructions of the American psychiatric profession.

Also, the brain just doesn’t work that way. It’s not about “high” this or “low” that. There are many chemicals in the brain interacting with each other in a very complex manner, with negative and positive feedback loops, so that there is no sense at all to say that anything in the brain relevant to any illness has to do with simply having too much or too little of any chemical.

Glory, glory hallelujah! - people are starting to understand.

I could go back and find the argument I had about this very point, but the other guy already admitted he was wrong and is no longer on the site, so gloating doesn't really help anyone. I'm just posting this for educational purposes. I wish this article was mandatory reading for all humans (right after a course in graduate-level statistics).

[Dukasaur]

So, what exactly is your point? Because our rudimentary attempts at finding explanations for mental illness thus far have failed, we should just throw in the towel and stop looking? We should just leave the sick alone and let them wither and die?

[jimboston]

I could go back and find the argument I had about this very point, but the other guy already admitted he was wrong and is no longer on the site, so gloating doesn't really help anyone. I'm just posting this for educational purposes. I wish this article was mandatory reading for all humans (right after a course in graduate-level statistics).

I say go back and find the original post and repost it and gloat. You’ve ‘earned’ it.

[jimboston]

So, what exactly is your point? Because our rudimentary attempts at finding explanations for mental illness thus far have failed, we should just throw in the towel and stop looking? We should just leave the sick alone and let them wither and die?

I propose the “suck it up buttercup” method to treating “mental illness”.

[DoomYoshi]

The point is that social constructions require social fixes. Psychiatry in its current state is about as valid scientifically as exorcism.

I would even go a step further and say that there can never be a pharmacological fix for mental illness. Not because brain chemistry is too complex, rather because it is too simple. There are only 11 or so neurotransmitters responsible for 100% of nervous system activity. Even if we start targeting individual receptors with greater accuracy (which has been the exclusive focus of this research for the past 30 years with almost no change in result), there will still be high levels of cascading side effects. A fix must be found elsewhere.

[DoomYoshi]

I could go back and find the argument I had about this very point, but the other guy already admitted he was wrong and is no longer on the site, so gloating doesn't really help anyone. I'm just posting this for educational purposes. I wish this article was mandatory reading for all humans (right after a course in graduate-level statistics).

I say go back and find the original post and repost it and gloat. You’ve ‘earned’ it.

Sure, just for you:
viewtopic.php?f=8&t=225376&start=100#p4986351

And dopamine IS CONCLUSIVELY linked to schizophrenia through too strong a correlation alone. What is put to question, and what the fuzz surrounding the dopamine hypothesis is about, is the causality between the two. The processes aren't fully comprehended, as you mentioned, but the existence of certain elements in or connected to the chain are known.

I really like how CONCLUSIVELY is all-capped.

[jusplay4fun]

NOT ONLY is the chemistry of the brain and nervous system complex, but there is another huge factor. And that is the differences and nuances for individuals. Most humans may react to chemical "Bx" one way, but a small percent of humans react this way instead, and even a smaller percentage that does THAT instead. Causality in human physiology is not 100%, as has been known for sometime. I read that about 5 years ago, meaning that those in medical research probably have known that for the past 10 years or so. And now, you do.

NO drug or vaccine, that I am aware, is 100% efficacious or effective, something I recall saying when the controversies about the COVID vaccines all began in January of 2021 or so. Pfizer and Moderna, at the VERY start, only claimed about 95% efficacy for their vaccine.

please read here:
https://www.conquerclub.com/forum/viewtopic.php?f=8&t=235925&p=5210247&hilit=efficacious#p5210247